{"id":114135,"date":"2022-06-13T23:50:51","date_gmt":"2022-06-13T23:50:51","guid":{"rendered":"http:\/\/www.hisark.com\/?p=114135"},"modified":"2022-06-13T23:50:51","modified_gmt":"2022-06-13T23:50:51","slug":"%eb%8f%99%ec%84%b1%ec%95%a0%ec%99%80-%ea%b3%bc%ed%95%99-7","status":"publish","type":"post","link":"http:\/\/www.hisark.com\/?p=114135","title":{"rendered":"\ub3d9\uc131\uc560\uc640 \uacfc\ud559 \u2013 7"},"content":{"rendered":"\n


\uc774\ubc88 \uc5f0\uc7ac\uc5d0\uc11c\ub294 \uc9c0\ub09c \uc5f0\uc7ac\uc5d0 \uc774\uc5b4 \ub3d9\uc131\uc560\uc758 \uc720\uc804\uc801 \uc5f0\uad6c\uc5d0 \ub300\ud55c \uacb0\uacfc\ub4e4\uc5d0 \ub300\ud574 \uc9c1\uc811\uc801\uc73c\ub85c \ubc1c\ud45c\ud55c \ub17c\ubb38\uc744 \uc911\uc2ec\uc73c\ub85c \uc870\uae08 \ub354 \uc0b4\ud3b4\ubcf4\uace0\uc790 \ud55c\ub2e4.<\/p>\n\n\n\n

1993\ub144, \uc138\uacc4 \ucd5c\uace0\uc758 \uacfc\ud559 \uc7a1\uc9c0 \uc911 \ud558\ub098\uc778 \u2018\uc0ac\uc774\uc5b8\uc2a4\u2019\uc5d0 \ub518 \ud574\uba38 \ubc15\uc0ac\uc758 \ub3d9\uc131\uc560 \uc720\uc804\uc790\uc5d0 \uad00\ud55c \ub0b4\uc6a9\uc774 \ubc1c\ud45c\ub418\uc790 \uc774\ub97c \uc5b8\ub860\ub4e4\uc774 \uacbd\uc7c1\uc801\uc73c\ub85c \ub300\uc11c\ud2b9\ud544\ud558\uc600\ub2e4. \uadf8\ub7ec\ub098 \uc774\ud6c4 \ub518 \ud574\uba38 \ubc15\uc0ac\ub294 \uacf5\ub3d9\uc5f0\uad6c\uac00\uc774\uc790 \ubbf8\uad6d \uc77c\ub9ac\ub178\uc774\uc8fc \uc2dc\uce74\uace0 \uc8fc\ub9bd\ub300\ud559\uc758 \uc815\uc2e0\uc758\ud559\uacfc \uad50\uc218\uc778 \ubb34\uc2a4\ud0c4\uc2a4\ud0a4 \ubc15\uc0ac\uac00 \uc8fc\ub3c4\ud55c 2005\ub144 \uc5f0\uad6c\ub17c\ubb38\uc5d0\uc11c \uc790\uc2e0\uc758 \uccab \ubc88\uc9f8 \uc5f0\uad6c1<\/sup> \uc5c5\uc801\uc73c\ub85c \ube5b\ub098\ub294 Xq28 \uc5fc\uc0c9\uccb4\uc640 \uc0c1\ubc18\ub418\ub294 \ub3d9\uc131\uc560 \ud6c4\ucc9c\uc131\uc5d0 \ub300\ud55c \uc9c0\uc9c0\ub97c \ud45c\uba85\ud558\uc600\ub2e4.<\/p>\n\n\n\n

\ud558\uc9c0\ub9cc \uc548\ud0c0\uae5d\uac8c\ub3c4 \uc5f0\uad6c\uc790 \uc790\uc2e0\uc758 \uc120\ud589 \uc5f0\uad6c\uc5d0 \ub300\ud574 \uc218\uc815\ub41c \uc758\uacac\uc784\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \uc5b8\ub860\ub4e4\uc740 \uc774\ub97c \ub300\uc911\uc5d0\uac8c \uc54c\ub9ac\uae30\ub97c \uc8fc\uc800\ud558\uc600\uc73c\uba70 \uc774\ub294 \uc624\ub298\uae4c\uc9c0\ub3c4 \ub9ce\uc740 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uc798\ubabb\ub41c \uc9c0\uc2dd\uc73c\ub85c \ub0a8\uc544 \uc788\ub2e4.<\/p>\n\n\n\n

\ube44\uc2b7\ud55c \uc2dc\uae30\uc778 1999\ub144, \uce90\ub098\ub2e4 \uc6e8\uc2a4\ud134 \uc628\ud0c0\ub9ac\uc624 \ub300\ud559 \uc815\uc2e0\uacfc\ud559\uacfc \uad50\uc218\uc778 \uc870\uc9c0 \ub77c\uc774\uc2a4\ubc15\uc0ac\ud300\uc740 \ud574\uba38 \ubc15\uc0ac\uac00 \ubc1c\ud45c\ud558\uc600\ub358 \u2018\uc0ac\uc774\uc5b8\uc2a4\u2019 4\uc6d4\ud638\uc5d0 \ud574\uba38 \ubc15\uc0ac\uc758 \uc5f0\uad6c\uacb0\uacfc\uc5d0 \ub300\ud574 \uc815\uba74\uc73c\ub85c \ubc18\ubc15\ud558\ub294 \uc5f0\uad6c\ub17c\ubb38 \u201c\ub0a8\uc131 \ub3d9\uc131\uc560: Xq28 \uc720\uc804\uc790\uc5d0\uc11c \ub9c8\uc774\ud06c\ub85c\uc0c8\ud2c0\ub77c\uc774\ud2b8 \ub9c8\ucee4\uc5d0 \ub300\ud55c \uc5f0\uacb0 \ubd80\uc7ac2<\/sup>\u201d \ub97c \ub2e4\uc74c\uacfc \uac19\uc740 \ub0b4\uc6a9\uc73c\ub85c \ubc1c\ud45c\ud558\uc600\ub2e4.<\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

\uba87 \uac00\uc9c0 \uc99d\uac70\uac00 \ub3d9\uc131\uc560\uc758 \uc720\uc804\uc801 \uc694\uc778\uc744 \uc5f0\ub8e8 \uc2dc\ud0a4\uace0 \uc788\ub2e4. \uac00\uc7a5 \uc8fc\ubaa9\ud560 \ub9cc\ud55c \uad00\ucc30\uc740 x \uc5fc\uc0c9\uccb4 \uc0c1\uc758 \ub9c8\uc774\ud06c\ub85c \uc0c8\ud2c0\ub77c\uc774\ud2b8(microsatellite) \ub9c8\ucee4\uc5d0 \ub300\ud55c \ub0a8\uc131 \ub3d9\uc131\uc560\uc758 \uc720\uc804\uc801 \uc5f0\uacb0\uc131\uc758 \ubcf4\uace0\uc600\ub2e4. \uc774 \uad00\ucc30\uc740 \ub354 \ub9ce\uc740 \uc5f0\uad6c\uc640 \ud655\uc778\uc744 \uc694\uad6c\ud558\uac8c \ub418\uc5c8\uc73c\uba70 Xq28 \uc5fc\uc0c9\uccb4\uc758 \uc704\uce58\uc758 \ub300\ub9bd \uc720\uc804\uc790 \uacf5\uc720\ub294 \uce90\ub098\ub2e4 \uac00\uc815\uc5d0\uc11c \uc120\ubc1c\ub41c 52\uba85\uc758 \ub3d9\uc131\uc560\uc790 \ud615\uc81c \uc30d\uc744 \ud45c\ubcf8\uc73c\ub85c \uc5f0\uad6c\ud558\uc600\ub2e4. Xq28\uc5d0\uc11c \ub124 \uac1c\uc758 \ub9c8\ucee4\uc5d0 (DXS1113, BGN, Factor 8, and DXS1108) \ub300\ud574 \ubd84\uc11d\ud558\uc600\uc73c\uba70, \uc774 \ub9c8\ucee4\uc5d0 \ub300\ud55c \ub300\ub9bd \ud615\uc9c8 \ubc0f \uc77c\uccb4 \ud615\uc9c8 \uacf5\uc720\ub294 \uc608\uc0c1\ubcf4\ub2e4 \uc99d\uac00\ud558\uc9c0 \uc54a\uc558\ub2e4. \uc774 \uacb0\uacfc\ub294 \ub0a8\uc131 \ub3d9\uc131\uc560\uc5d0 \ubc14\ud0d5\uc744 \ub454 X \uc5fc\uc0c9\uccb4 \uc720\uc804\uc790\uc758 \uc5f0\uad00\uc131\uc744 \uc9c0\uc9c0\ud558\uc9c0 \uc54a\ub294\ub2e4.<\/strong><\/p>\n\n\n\n

\uadf8\ub9ac\uace0 \uc800\uc790\uc778 \ub77c\uc774\uc2a4 \ubc15\uc0ac\ub294 \ub17c\ubb38\uc758 \ub9c8\uc9c0\ub9c9 \ubd80\ubd84\uc5d0\uc11c \ub2e4\uc74c\uacfc \uac19\uc740 \ub9d0\ub85c\uc368 \ub17c\ubb38\uc744 \ub9c8\ubb34\ub9ac\ud558\uace0 \uc788\ub2e4.<\/p>\n\n\n\n

\uc6b0\ub9ac\uc758 \uc5f0\uad6c \uacb0\uacfc\uac00 \uc65c 1993\ub144 \uc0ac\uc774\uc5b8\uc2a4\uc5d0 \ubc1c\ud45c\ud55c Xq28 \uc5fc\uc0c9\uccb4\uc758 \ub3d9\uc131\uc560 \uc720\uc804\uc801 \uc99d\uac70\uc5d0 \ub300\ud55c3 <\/sup>\ud574\uba38 \ubc15\uc0ac\uc758 \uc6d0\ub798 \uc5f0\uad6c\uc640 \ub2e4\ub978\uc9c0\ub294 \ubd88\ubd84\uba85\ud558\ub2e4. \ud558\uc9c0\ub9cc \uc5f0\uad6c \ub300\uc0c1 \ud45c\ubcf8\uc758 \ud06c\uae30\uc5d0\uc11c \uc6b0\ub9ac\uc758 \uc5f0\uad6c\uac00 \ud574\uba38 \ubc15\uc0ac\uc758 \uc5f0\uad6c\ubcf4\ub2e4 \ud6e8\uc52c \ucef8\uae30 \ub54c\ubb38\uc5d0, \uadf8 \uc2e0\ub8b0\uc131\uc5d0 \uc788\uc5b4\uc11c \ud574\uba38 \ubc15\uc0ac\uc758 \uc5f0\uad6c\uc5d0\uc11c \ubcf4\uace0 \ub41c \uac83 \ubcf4\ub2e4\uc720\uc804 \ud6a8\uacfc\ub97c \ub354 \uc798 \uac10\uc9c0\ud560 \uc218 \uc788\ub294 \uc801\uc808\ud55c \uc5f0\uad6c \uc2e0\ub8b0\ub3c4\ub97c \ud655\uc2e4\ud788 \ud655\ubcf4\ud558\uc600\ub2e4\uace0 \ud560 \uc218 \uc788\ub2e4. \uadf8\ub7fc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \uc6b0\ub9ac\uc758 \ub370\uc774\ud130\ub294 Xq28 \uc5fc\uc0c9\uccb4 \uc704\uce58\uc5d0 \ud06c\uac8c \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uc720\uc804\uc790\uc758 \uc874\uc7ac\ub97c \ub4b7\ubc1b\uce68\ud558\uc9c0 \ubabb\ud55c\ub2e4. \ube44\ub85d \uc6b0\ub9ac\uc758 \uc5f0\uad6c\uc5d0\uc11c Xq28\uc5d0 \ub300\ud55c \uc131\uc801 \uc9c0\ud5a5\uc758 \uc5f0\uad00\uc131\uc5d0 \ub300\ud55c \uc5b4\ub5a0\ud55c \uc99d\uac70\ub3c4 \ubc1c\uacac\ud558\uc9c0 \ubabb\ud588\uc9c0\ub9cc,\uc774\ub7ec\ud55c \uacb0\uacfc\ub294 \uac8c\ub188\uc758 \ub2e4\ub978 \uacf3\uc5d0\uc11c \uac80\ucd9c \uac00\ub2a5\ud55c \uc720\uc804\uc790 \ud6a8\uacfc\uc758 \uac00\ub2a5\uc131\uc744 \ubc30\uc81c\ud558\uc9c0\ub294 \uc54a\ub294\ub2e4.<\/strong><\/p>\n\n\n\n

\ud558\uc9c0\ub9cc \ud574\uba38 \ubc15\uc0ac\uc758 \uc5f0\uad6c\uacb0\uacfc\uc640 \uc0c1\ubc18\ub41c \uc5f0\uad6c\uacb0\uacfc\ub97c \ubc1c\ud45c\ud55c \ub77c\uc774\uc2a4 \ubc15\uc0ac\uc758 \ub17c\ubb38\uc740 1993\ub144 \ud574\uba38 \ubc15\uc0ac\uc758 \ub17c\ubb38\uacfc\ub294 \uc0c1\ub2f9\ud788 \ub2e4\ub974\uac8c \uc5b8\ub860\uc758 \ubb34\ubc18\uc751\uc744 \uacbd\ud5d8\ud558\uac8c \ub41c\ub2e4. \uc774\ub7ec\ud55c \uc5b8\ub860\uc758 \ubb34\uad00\uc2ec\uc740 \ub3d9\uc131\uc560\uc758 \uc720\uc804\uc801 \uc694\uc778\uc5d0 \ub300\ud55c \uc77c\ubc18\uc778\ub4e4\uc758 \uc0dd\uac01\uc744 \ud55c\ucabd\uc73c\ub85c \uace0\ucc29\uc2dc\ud0a4\uae30\uc5d0 \ucda9\ubd84\ud55c \uc601\ud5a5\ub825\uc744 \ubc1c\ud718\ud558\uc600\uc73c\ub9ac\ub77c \uc9d0\uc791\ud55c\ub2e4. \ub77c\uc774\uc2a4 \ubc15\uc0ac \ub610\ud55c \uc2dc\ub300\uc801 \ud76c\uc0dd\ubb3c\uc774 \ub418\uc9c0 \uc54a\uae30 \uc704\ud574 \ub3d9\uc131\uc560\uc758 \uc720\uc804\uc790 \ud6a8\uacfc\uc758 \uac00\ub2a5\uc131\uc5d0 \ub300\ud574 \uc644\uc804\ud788 \ubc30\uc81c\ud558\uc9c0\ub294 \uc54a\uc558\ub2e4.\uc704\uc5d0\uc11c \uac1c\ub7b5\uc801\uc778 \uc774\uc57c\uae30\ub9cc \ub098\ub208 \ubb34\uc2a4\ud0c4\uc2a4\ud0a4 \ubc15\uc0ac\ud300\uc758 2005\ub144 \uc5f0\uad6c \u201c\ub0a8\uc131\uc758 \uc131\uc801 \uc9c0\ud5a5\uc5d0 \ub300\ud55c \uc720\uc804\uccb4 \uac80\uc0ac1<\/sup>\u201d\uc758 \ub0b4\uc6a9\uc744 \uc0b4\ud3b4\ubcf4\uba74 \ub2e4\uc74c\uacfc \uac19\ub2e4.<\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

\ubcf8 \uc5f0\uad6c\ub294 \ub0a8\uc131\uc758 \uc131\uc801 \uc9c0\ud5a5\uc5d0 \ub300\ud55c \uc644\uc804\ud55c \uac8c\ub188 \uc870\uc0ac\uc758 \uccab \ubc88\uc9f8 \ubcf4\uace0\uc11c\uc774\ub2e4. \ub450 \uba85\uc774\uc0c1\uc758 \uac8c\uc774 \ud615\uc81c\uac00 \uc788\ub294 146\uac00\uad6c\uc5d0\uc11c 456\uba85\uc744 \ub300\uc0c1\uc73c\ub85c 403\uac1c\uc758 \ub9c8\uc774\ud06c\ub85c \uc0c8\ud2c0\ub77c\uc774\ud2b8 (microsatellite) \ub9c8\ucee4\ub85c 10-cM (centimorgan; cM, \uc720\uc804\uc801 \uc5f0\uacc4\uc131\uc744 \ub098\ud0c0\ub0b4\ub294 \ub2e8\uc704)\uc758 \uac04\uaca9\uc73c\ub85c \uc720\uc804\uc790\ud615\uc744 \uacb0\uc815\ud558\uc600\ub2e4. \uc774\uc804\uc758 \ubcf4\ub3c4\uc5d0 \uc758\ud558\uc5ec \ubaa8\uacc4\uc5d0 \uc758\ud574 \uc720\uc804\ub418\ub294 \uc131\uc801 \uc131\ud5a5\uc774 \uc0c1\uc5fc\uc0c9\uccb4 (autosome) \uc720\uc804\uc790\uc5d0 \uc791\uc6a9\ud558\ub294 \ud6c4\uc0dd\uc720\uc804\uc801 \uc778\uc790\uc5d0 \uc758\ud574 \ub098\ud0c0\ub0a0 \uc218 \uc788\ub2e4\ub294 \uc774\uc804\uc758 \ubcf4\uace0\uc5d0 \ub530\ub77c, \uac00\uc7a5 \uadfc\uc811\ud55c \ucd94\uc815\uce58\uc758 mlod \uc810\uc218 (multipoint lod score; mlod score, \ub450 \uac1c\uc758 \uc720\uc804\uc790\uc758 \uc704\uce58\uac00 \uc5fc\uc0c9\uccb4\uc5d0\uc11c \uc11c\ub85c \uac00\uae5d\uac8c \uc704\uce58\ud560 \uac00\ub2a5\uc131\uc774 \uc788\ub294\uc9c0\uc5d0 \ub300\ud55c \ud1b5\uacc4\ud559\uc801 \ud3c9\uac00\ub85c \uc774\ub294 \ud55c \uc30d\uc758 \uc720\uc804\uc790\ub85c \ud568\uaed8 \uc0c1\uc18d\ub420 \uac00\ub2a5\uc131\uc774 \uc788\uc74c\uc744 \ub098\ud0c0\ub0b4\ub294 \uc218\uce58\uc774\ub2e4)\ub97c \ubaa8\uacc4, \ubd80\uacc4 \uadf8\ub9ac\uace0 \ubcf5\ud569 \uc720\uc804\uc73c\ub85c \ubd84\ub9ac\ud558\uc5ec \uacc4\uc0b0\ud558\uc600\ub2e4.<\/strong><\/p>\n\n\n\n

\uac00\uc7a5 \ub192\uc740 mlod \uc810\uc218\ub294 D7S798 \uadfc\ucc98\uc758 \uc704\uce58\uc5d0\uc11c 3.45\uc774\uc5c8\uace0, \ubaa8\uacc4\uc640 \ubd80\uacc4\uc758 \ubcf5\ud569 \uc720\uc804\uc758 \uae30\uc5ec\ub3c4\uc640 \uac70\uc758 \ub3d9\uc77c\ud558\uc600\ub2e4. \ub450 \ubc88\uc9f8\ub85c \ub192\uc740 mlod \uc810\uc218 1.96\uc740 8q12\uc5d0\uc11c D8S505 \uadfc\ucc98\uc5d0 \uc788\uc5c8\uc73c\uba70, \uac00\uc7a5 \ub192\uc740 \uac12\uacfc \ub9c8\ucc2c\uac00\uc9c0\ub85c \ubaa8\uacc4\uc640 \ubd80\uacc4\uc758 \ub3d9\uc77c\ud55c \uc720\uc804 \uae30\uc5ec\ub3c4\uac00 \uc788\uc5c8\ub2e4. \ubaa8\uacc4\uc5d0 \uc758\ud55c \uc720\uc804 \ud6a8\uacfc\ub294 10q26\uc5d0\uc11c \ub9c8\ucee4 D10S217 \uadfc\ucc98\uc5d0\uc11c \ubc1c\uacac\u00a0\ub418\uc5c8\uace0, \ubaa8\uacc4\uc758 \uae30\uc5ec\ub3c4\uc5d0 \ub300\ud55c mlod \uc810\uc218\ub294 1.81\uc774\uc5c8\uace0 \ubd80\uacc4\uc758 \uae30\uc5ec\ub3c4\ub294 \uc5c6\uc5c8\ub2e4. \uc6b0\ub9ac\ub294 \uc804\uccb4 \ud45c\ubcf8\uc5d0\uc11c Xq28\uc5d0 \ub300\ud55c \uc5f0\uad00\uc131\uc744 \ubc1c\uacac\ud558\uc9c0\ub294 \ubabb\ud588\uc9c0\ub9cc \uc774 \uad6c\uac04\uc5d0\uc11c \uc774\uc804\uc5d0 \ubcf4\uace0 \ub41c \uc5f0\uad00\uc131\uc758 \uc99d\uac70\ub97c \ud1a0\ub300\ub85c \uc774 \uc5f0\uad6c \uacb0\uacfc\ub97c \uba85\ud655\ud788 \ud558\uae30 \uc704\ud574 \ubcf4\uc644 \ubd84\uc11d\uc744 \uc2e4\uc2dc\ud558\uc600\ub2e4. \uba3c\uc800, \uc774\uc804\uc5d0 \ubcf4\uace0\ub41c \ub370\uc774\ud130\ub97c \ub2e4\uc2dc \ubd84\uc11d\ud55c \uacb0\uacfc 6.45\uc758 mlod \uc810\uc218\ub97c \ud655\uc778\ud558\uc600\ub2e4. \uadf8\ub9ac\uace0 \uc774\uc804\uc5d0 \ubcf4\uace0 \ub41c \uac00\uc871\ub4e4\ub85c \ud45c\ubcf8\uc744 \uc81c\ud55c \ud6c4\uc5d0 \ud604\uc7ac\uc758 \uc790\ub8cc\ub4e4\ub85c \uc7ac \ubd84\uc11d\ud55c \uacb0\uacfc 1.99\uc758 mlod \uc810\uc218\ub97c \ud655\uc778\ud558\uc600\ub2e4. \uc774 Xq28 \uacb0\uacfc\ub294 \ubcf8\ubb38\uc5d0\uc11c \uc790\uc138\ud788 \ub17c\uc758\ub429\ub2c8\ub2e4. \ub0a8\uc131\uc5d0\uac8c \uc788\uc5b4\uc11c \uc131\uc801 \uc9c0\ud5a5\uc758 \ud589\ub3d9 \ud2b9\uc131\uc758 \uc815\uc0c1\uc801\uc778 \ubcc0\ud654\uc5d0 \ub300\ud55c \uc774 \uccab \ubc88\uc9f8 \uac8c\ub188 \uc870\uc0ac\uc758 \uacb0\uacfc\ub294 \uc81c\uc548\ub41c \uc5fc\uc0c9\uccb4 \uad6c\uac04 \ub0b4\uc5d0\uc11c \ubc00\ub3c4\uac00 \ub192\uc740 \uc5f0\uacc4 \uc9c0\ub3c4\ub97c \uac00\uc9c4 \uc0c8\ub85c\uc6b4 \uc0d8\ud50c\uc5d0 \ub300\ud574 \uc774\ub7ec\ud55c \uacb0\uacfc\ub97c \uc7ac\ud604\ud558\ub824\ub294 \ub178\ub825\uc744 \uacc4\uc18d \uae30\uc6b8\uc5ec\uc57c \ud55c\ub2e4.\u00a0<\/strong><\/p>\n\n\n\n

\ubc1c\ud45c \ub0b4\uc6a9\uacfc \uac19\uc774 \ubb34\uc2a4\ud0c4\uc2a4\ud0a4 \ubc15\uc0ac, \ud574\uba38 \ubc15\uc0ac \ubc0f \uadf8\uc758 \ub3d9\ub8cc \uc5f0\uad6c\uc790\ub4e4\uc740 \uc774 \uc5f0\uad6c\ub97c \ud1b5\ud558\uc5ec Xq28 \uc5fc\uc0c9\uccb4\uc640 \ub3d9\uc131\uc560\uc640\uc758 \uad00\ub828\uc131\uc740 \ud655\uc778\ud558\uc9c0 \ubabb\ud558\uc600\uc73c\ub098 \uc774\ub97c \ubcf4\uc644\ud560 \uc218 \uc788\ub294 \uc720\uc0ac \uc2e4\ud5d8\uc758 \uac00\ub2a5\uc131\uc5d0 \ub300\ud574 \uc5b8\uae09\ud558\uba70 \ud574\uba38 \ubc15\uc0ac\uc758 \uccab \ubc88\uc9f8 \uc2e4\ud5d8\uc758 \uc624\ub958\uc5d0 \ub300\ud574 \uc5d0\ub458\ub7ec \ud45c\ud604\ud558\uace0 \uc788\ub2e4. \uadf8\ub7ec\uba74\uc11c \ub2e4\uc74c\uacfc \uac19\uc740 \ud45c\ud604\uc73c\ub85c \ub17c\ubb38\uc758 \uacb0\ub860\uc744 \ub0b4\ub9ac\uace0 \uc788\ub2e4.\u00a0<\/p>\n\n\n\n

\uc694\uc57d\ud558\uba74, \uc6b0\ub9ac\ub294 \ub0a8\uc131\uc758 \uc131\uc801 \uc9c0\ud5a5\uc758 \ubcf5\uc7a1\ud558\uace0 \ubcf5\ud569\uc801\uc778 \uc720\uc804 \ud45c\ud604\ud615\uc5d0 \uad00\ub828\ub41c \uc720\uc804\uc790\uc758 \uc790\ub9ac\ub4e4\uc5d0 \ub300\ud574 \uccab \ubc88\uc9f8 \uac8c\ub188 \uc870\uc0ac\ub97c \ubcf4\uace0 \ud558\uc600\uc2b5\ub2c8\ub2e4. \uc6b0\ub9ac\ub294 \ubbf8\ub798\uc758 \uc5f0\uad6c\ub97c \uc704\ud558\uc5ec \uba87 \uac00\uc9c0 \uc5fc\uc0c9\uccb4\uc758 \uc704\uce58\uc640 \ud6c4\ubcf4 \uc720\uc804\uc790\ub4e4\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4. \uc131\uc801 \uc9c0\ud5a5\uc5d0 \uad00\ub828\ub41c \uc720\uc804\uc790\uc758 \ubd84\uc11d\uc740 \uc778\uac04\uc758 \ub2e4\uc591\uc131, \uc9c4\ud654 \ubc0f \ub450\ub1cc \ubc1c\ub2ec\uc5d0 \ub300\ud55c \uc6b0\ub9ac\uc758 \uc774\ud574\ub97c \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uba85\ud655\ud55c \ub3d9\ubb3c \ubaa8\ub378\uc774 \uc5c6\ub294 \uacbd\uc6b0 \uc720\uc804\uc801 \uc5f0\uacc4\uc5d0 \ub300\ud55c \uc5f0\uad6c\uac00 \uc774\ub4e4 \uc720\uc804\uc790\ub4e4\uc758 \uc704\uce58\ub97c \ubc1c\uacac\ud560 \uc218 \uc788\ub294 \ucd5c\uc0c1\uc758 \uae30\ud68c\ub97c \uc81c\uacf5\ud560 \uac83\uc785\ub2c8\ub2e4.<\/strong><\/p>\n\n\n\n

\uc774\ubc88 \uc5f0\uc7ac\uc758 \ub9c8\uc9c0\ub9c9\uc73c\ub85c\ub294 2010\ub144 \uc2a4\uc6e8\ub374\uc758 \ub791\uc2a4\ud2b8\ub86c (Niklas Langstrom, M.D., Ph.D.) \ubc15\uc0ac\ud300\uc758 \uc5f0\uad6c \u201c\ub3d9\uc131\uc560 \uc131 \ud589\ub3d9\uc5d0 \ub300\ud55c \uc720\uc804\uc801 \ubc0f \ud658\uacbd\uc801 \uc601\ud5a5:\uc2a4\uc6e8\ub374\uc758 \uc30d\ub465\uc774 \uc778\uad6c \uc5f0\uad6c4<\/sup>\u201d\uc5d0 \ub300\ud574 \uc0b4\ud3b4\ubcf4\uace0\uc790 \ud55c\ub2e4. \uc774\uc5f0\uad6c \ub17c\ubb38\uc5d0\uc11c \ub791\uc2a4\ud2b8\ub86c \ubc15\uc0ac\ub294 \ub3d9\uc131\uc758 \uc131\uc801 \ud589\ub3d9\uc774 \uc720\uc804\uacfc \ud658\uacbd \ubaa8\ub450\uc5d0 \uc788\ub2e4\uace0 \ub2e4\uc74c\uacfc \uac19\uc774 \ubc1c\ud45c\ud558\uc600\ub2e4.<\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

\uc778\uac04\uc758 \uc131\uc801 \ucde8\ud5a5\uc5d0 \ub300\ud55c \uc720\uc804\uc790\uc640 \ud658\uacbd\uc758 \uc0c1\ub300\uc801 \uc911\uc694\uc131\uc5d0 \ub300\ud574\uc11c\ub294 \uc5ec\uc804\ud788 \ubd88\ud655\uc2e4\uc131\uc774 \uc874\uc7ac\ud55c\ub2e4. \ud55c \uac00\uc9c0 \uc774\uc720\ub294 \uc774\uc804\uc758 \ud1b5\uacc4\ub294 \uc790\uac00 \uc120\ud0dd \uc2dd, \uae30\ud68c\uc8fc\uc758 \uc2dd, \ud639\uc740 \uc791\uc740 \uc778\uad6c \uc9d1\ub2e8\uc758 \uc0d8\ud50c\uc744 \uc0ac\uc6a9\ud588\uae30 \ub54c\ubb38\uc774\ub2e4. \uc6b0\ub9ac\ub294 \uc9c0\uae08\uae4c\uc9c0 \uc2dc\ub3c4\ub41c \ub3d9\uc131 \uac04\uc758 \uc131\ud589\uc704\uc5d0 \uad00\ud55c \uac00\uc7a5 \ud070 \ud45c\ubcf8 \uc9d1\ub2e8\uc758 \uc30d\ub465\uc774 \uc5f0\uad6c\ub97c \uc218\ud589\ud558\uae30 \uc704\ud574 \uc2a4\uc6e8\ub374\uc758 \ubaa8\ub4e0 \uc131\uc778 \uc30d\ub465\uc774 (20-47\uc138)\uc5d0 \ub300\ud55c 2005-2006\ub144\ub3c4 \uc2e4\uc9c8\uc801 \uc778\uad6c \ud1b5\uacc4 \uc870\uc0ac \uc790\ub8cc\ub97c \uc0ac\uc6a9\ud558\uc600\ub2e4. \uc6b0\ub9ac\ub294 \ud3c9\uc0dd \ub3d9\uc131 \ud30c\ud2b8\ub108\uc758 \uc77c\uc815 \ubd80\ubd84 \uadf8\ub9ac\uace0 \uc804\uccb4\uc758 \ub370\uc774\ud130\uc5d0 \ub300\ud574 \uc0dd\uccb4 \uc778\uc2dd \uce21\uc815 \ubaa8\ub378\ub9c1\uc744 \uc218\ud589\ud558\uc600\ub2e4. \ubd84\uc11d\uc740 \uc131\ubcc4\ub85c \ub098\ub204\uc5b4 \uc2e4\uc2dc\ud558\uc600\ub2e4. \uc30d\ub465\uc774\uc758 \uc720\uc0ac\uc131\uc740 3,826\uba85\uc744 \ub300\uc0c1\uc73c\ub85c \uc5f0\uad6c\ub41c \uc77c\ub780\uc131 \uc30d\ub465\uc774\uc640 \uc774\ub780\uc131 \uc30d\ub465\uc774\uc5d0 \ub300\ud574 \uc801\ub2f9\ud788 \ubd84\ud3ec\ub418\ub294 \uac83\uc73c\ub85c \uc870\uc0ac\ub418\uc5c8\ub2e4.\uc0dd\uccb4 \uc778\uc2dd \uce21\uc815 \ubaa8\ub378\ub9c1\uc5d0 \ub530\ub974\uba74 \ub0a8\uc131\uc758 \uc720\uc804\uc801 \uc601\ud5a5\uc740 \ubd84\uc0b0\uc758 .34-.39, \uacf5\uc720 \ub41c \ud658\uacbd\uc740 .00, \uac1c\ubcc4\uc801\uc778 \ud2b9\ubcc4\ud55c \ud658\uacbd\uc5d0 \uc758\ud55c \uc601\ud5a5\uc740 \ubd84\uc0b0\uc758 .61-.66\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \uc5ec\uc131\uc758 \uc0c1\uc751\ud558\ub294 \ucd94\uc815\uce58\ub294 \uc720\uc804\uc801 \uc694\uc778\uc5d0 \ub300\ud574\uc11c\ub294 .18-.19, \uacf5\uc720\ub41c \ud658\uacbd\uc758 \uc694\uc778\uc5d0 \ub300\ud574\uc11c\ub294 .16-.17, \uadf8\ub9ac\uace0 \uac1c\ubcc4\uc801\uc778 \ud2b9\ubcc4\ud55c \ud658\uacbd\uc758 \uc694\uc778\uc5d0 \ub300\ud574\uc11c\ub294 .64-.66 \uc774\uc5c8\ub2e4. \ube44\ub85d \uac01\uac01\uc758 \uc694\uc778\uc5d0 \ub300\ud55c \uc2e0\ub8b0\ub3c4\uc758 \uad6c\uac04\uc774 \ub113\uc5b4 \uc2e0\uc911\ud55c \ud574\uc11d\uc744 \uc694\uad6c\ud558\uae30\ub294 \ud558\uc9c0\ub9cc \uadf8 \uacb0\uacfc\ub294 \ub3d9\uc131\uc758 \uc131\uc801 \ud589\uc704\uc5d0 \ub300\ud574 \uc120\ucc9c\uc801 \uc720\uc804\uacfc \uce5c\uc219\ud568<\/strong><\/p>\n\n\n\n

\uc774 \uc911\uac04 \uc815\ub3c4\uc758 \uc601\ud5a5\uc744 \ubbf8\uce58\uba70,\uadf8\ub9ac\uace0 \uc0ac\ud68c\uc801 \ubc0f \uc0dd\ubb3c\ud559\uc801 \ube44\uacf5\uc720 \ud658\uacbd\uc774 \ub3d9\uc131\uc758 \uc131\uc801 \ud589\uc704\uc5d0 \uc911\uac04 \uc815\ub3c4 \ud639\uc740 \uadf8 \uc774\uc0c1\uc758 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4\ub294 \uac83\uc5d0 \ub300\ud574 \uc77c\uad00\ub41c \uacb0\uacfc\ub97c \ub098\ud0c0\ub0b8\ub2e4.<\/strong><\/p>\n\n\n\n

\ub791\uc2a4\ud2b8\ub86c \ubc15\uc0ac\ub294 \uadf8\uc758 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc704\uc758 \uacb0\uacfc\ub4e4\uc744 \uc124\uba85\ud55c \ud6c4 \ub2e4\uc74c\uacfc \uac19\uc774 \ub05d\ub9fa\ub294\ub2e4.<\/p>\n\n\n\n

\uacb0\ub860\uc801\uc73c\ub85c \uc2e0\ub8b0 \uad6c\uac04\uc774 \ub113\uae30\ub294 \ud558\uc9c0\ub9cc \uc6b0\ub9ac\ub294 \uc774 \uc5f0\uad6c\ub97c \ud1b5\ud574 \ub3d9\uc131\uc758 \uc131\uc801 \ud589\uc704\uc5d0 \ub300\ud55c \uc720\uc804\uc801 \ubc0f \ube44 \uc720\uc804\uc801 \uc694\uc18c\ub4e4\uc5d0 \ub300\ud55c \uc601\ud5a5\ub825\uc5d0 \ub300\ud574 \ud604\uc7ac\uae4c\uc9c0 \uc81c\uc2dc\ub41c \uc5f0\uad6c \uc911 \uac00\uc7a5 \ud3b8\uacac\uc774 \uc5c6\ub294 \uc5f0\uad6c \uacb0\uacfc\ub97c \uc81c\uc2dc\ud55c\ub2e4\uace0 \ubbff\ub294\ub2e4. \uc774\uc0c1\uc758 \uacb0\uacfc\ub4e4\uc740 \uc774 \ubcf5\uc7a1\ud55c \ud2b9\uc9d5\uc801 \ud604\uc0c1\uc5d0 \ub300\ud574 \ub354 \uae4a\uc740 \uc5f0\uad6c\uac00 \ud544\uc694\ud568\uc744 \uc81c\uc2dc\ud55c\ub2e4.<\/strong><\/p>\n\n\n\n

\uc704\uc758 \ub791\uc2a4\ud2b8\ub86c \ubc15\uc0ac\uc758 \ub9c8\uc9c0\ub9c9 \uacb0\ub860\uc744 \ubcf4\uba74 \ub3d9\uc131\uc560\uc5d0 \ub300\ud55c \uacfc\ud559\uc801 \ud574\uc11d\uc774 Xq28 \uc5fc\uc0c9\uccb4\uc5d0 \uc758\ud55c \u201c\uc720\uc804\uc801\u201d \ud604\uc0c1\uc774\ub77c\ub294 \uac15\ub825\ud55c \uc8fc\uc7a5\uc774 \uc810\ucc28 \uc1e0\ud1f4\ud558\uace0 \uc774\uc81c\ub294 \ubcf5\ud569\uc801\uc778 \uc720\uc804\ud615\uc9c8, \ub354 \ub098\uc544\uac00 \ud658\uacbd\uc801\uc778 \uc694\uc778\uc774 \ud568\uaed8 \uc791\uc6a9\ud558\uace0 \uc788\ub2e4\ub294 \uc8fc\uc7a5\uc73c\ub85c \uadf8 \ucd08\uc810\uc774 \uc62e\uaca8\uac00\uace0 \uc788\uc74c\uc744 \ubcfc \uc218\uac00 \uc788\ub2e4.<\/p>\n\n\n\n

\ub9c8\uc9c0\ub9c9 \uc5f0\uc7ac\uc5d0\uc11c\ub294 \uc9c0\uae08\uae4c\uc9c0\uc758 \ub0b4\uc6a9\ub4e4\uc744 \uac00\ubccd\uac8c \uc0b4\ud3b4\ubcf4\uace0 \uac00\uc7a5 \ucd5c\uadfc\uc5d0 \ubc1c\ud45c\ub418\uace0 \uc788\ub294 \uc5f0\uad6c \ub0b4\uc6a9\uc5d0 \ub300\ud574 \uc0b4\ud53c\uba74\uc11c \u2018\ub3d9\uc131\uc560\uc640 \uacfc\ud559\u2019\uc5d0 \ub300\ud55c \uc5f0\uc7ac\ub97c \ub9c8\uac10\ud558\uace0\uc790 \ud55c\ub2e4.<\/p>\n\n\n\n

—————————————-<\/p>\n\n\n\n

\ucc38\uace0\ubb38\ud5cc<\/p>\n\n\n\n

1. Mustanski, Brian S.; DuPree, Michael G.; Nievergelt, Caroline M.; Bocklandt, Sven; Schork, Nicholas J.; Hamer, Dean H. A genomewide scan of male sexual orientation. Human Genetics, 2005;116(4): 272-278.<\/p>\n\n\n\n

2. Rice, George; Anderson, Carol; Risch, Neil; Ebers, George. Male Homosexuality: Absence of Linkage to Microsatellite Makers at Xq28. Science, 1999;284(5414): 665-667.<\/p>\n\n\n\n

3.  Hamer, Dean; Hu, Stella; Magnuson, Victoria L.; Hu, Nan; Pattatucci, Angela M. A linkage between DNA markers on the X chromosome and male sexual orientation. Science, 1993;261: 321-327.<\/p>\n\n\n\n

4. Langstrom, Niklas; Rahman, Qazi; Carlstrom, Eva. Genetic and Environement Effects on Same-sex Sexual Behavior: A Population Study of Twins in Sweden. Archives of sexual behavior, 2010;39(1): 75-80.<\/p>\n","protected":false},"excerpt":{"rendered":"

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